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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Monoamine Oxidase B inhibitor 2
- 库存:
10
- 供应商:
TargetMol
- 规格:
50 mg/25 mg/100 mg
| 规格: | 50 mg | 产品价格: | ¥13800.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥10600.0 |
| 规格: | 100 mg | 产品价格: | ¥17500.0 |
Product Introduction
Bioactivity
英文名:Monoamine Oxidase B inhibitor 2
描述:Monoamine Oxidase B inhibitor 2 is a potent, reversible, orally active and selective inhibitor of monoamine oxidase B (MAO-B) (IC50 = 1.33 nM) which can across the blood-brain barrier (BBB). Monoamine Oxidase B inhibitor 2 shows antioxidant and anti-neuroinflammatory activities which can be used in the study of Parkinson’s disease [1].

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文献和实验Monoamine oxidase (MAO; EC 1.4:3.4; amine: oxygen oxidoreductase; deaminating; flavine-containing) is an enzyme that oxidizes a variety of monoamine neurotransmitters and neuromodulators, as well as exogenous bioactive monoamines
Translocation of p47phox and Activation of NADPH Oxidase in Mononuclear Cells
, we have demonstrated that glucose challenge causes an increase in ROS generation by MNC and polymorphonuclear cells (PMNL). We have also demonstrated that the suppression of ROS generation by MNC by diphenylene iodonium (DPI), a specific inhibitor of NADPH oxidase
of benzodiazepine and barbiturate anxiolytic agents. In several animal models for anxiety (social interaction, elevated plus maze, and potentiated startle), three weeks of repeated daily treatment with tricyclic (TCA) or monoamine oxidase inhibitor (MAOI
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