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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Topoisomerase I inhibitor 3
- 库存:
10
- 供应商:
TargetMol
- CAS号:
2588211-50-9
- 规格:
100 mg/50 mg/25 mg
| 规格: | 100 mg | 产品价格: | ¥17500.0 |
|---|---|---|---|
| 规格: | 50 mg | 产品价格: | ¥13800.0 |
| 规格: | 25 mg | 产品价格: | ¥10600.0 |
Product Introduction
Bioactivity
英文名:Topoisomerase I inhibitor 3
描述:Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase. Topoisomerase I inhibitor 3 is an inhibitor of topoisomerase I that interact with topoisomerase I-DNA complex [1].

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文献和实验Analysis of Cleavage Complexes Using Reactive Inhibitor Derivatives
only with the base pairs immediately adjacent to the scissile phosphodiester bond and only in the presence of topoisomerase, providing strong and direct evidence that the DNA substrate forms an important component of the inhibitor binding site.
The Dynamics of DNA Topoisomerase II in Living Cells
Here, we describe methods to prepare a mammalian expression plasmid encoding EGFP fused to the amino-terminus of human DNA topoisomerase IIα (Topo IIα) for use in studying the dynamics of Topo IIα in living cells. In previous studies
Methods to Assay Inhibitors of DNA Gyrase and Topoisomerase IV Activities
DNA gyrase and DNA topoisomerase (topo) IV are the bacterial targets of coumarin and quinolone antimicrobial agents. Widespread resistance to clinically important antibiotics such as beta-lactams and macrolides has stimulated the development
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