- ￥932 - 26700
- TargetMol
- 美国
- T60336
- 2025年07月13日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
CCR4 antagonist 3-1
- 库存：
10
- 供应商：
TargetMol
- CAS号：
1957-01-3
- 规格：
500 mg/10 mg/50 mg/5 mg/25 mg/100 mg/1 mg
| 规格： | 500 mg | 产品价格： | ￥26700.0 |
|---|---|---|---|
| 规格： | 10 mg | 产品价格： | ￥3730.0 |
| 规格： | 50 mg | 产品价格： | ￥9870.0 |
| 规格： | 5 mg | 产品价格： | ￥2320.0 |
| 规格： | 25 mg | 产品价格： | ￥7320.0 |
| 规格： | 100 mg | 产品价格： | ￥13300.0 |
| 规格： | 1 mg | 产品价格： | ￥932.0 |
Product Introduction
Bioactivity
英文名:CCR4 antagonist 3-1
描述:CCR4 antagonist 3-1 is a less active chemokine receptor 4 (CCR4) antagonist that inhibits [125I]TARC (thymus and activation-regulated chemokine) with an IC50 value of 1.7 μM. CCR4 antagonist 3-1 inhibits the binding of radiolabeled [125I]TARC and macrophage-derived chemokine ( MDC) to CEM cell surface and inhibits TARC-mediated CEM cell migration in vitro with an IC50 value of 6.4 μM. CCR4 antagonist 3 inhibited the binding of radiolabeled [125I]TARC and macrophage-derived chemokine (MDC) to the CCR4 receptor on the surface of CEM cells and inhibited TARC-mediated migration of CEM cells in vitro with an IC50 value of 6.4 μM.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Characterization of Chemokine Receptors
a whole‐cell assay. The competition is homologous in that the radiolabeled and unlabeled ligand are both human TARC, which is species cross‐reactive such that it also binds to the murine CCR4 receptor. The IC50 value obtained in this experiment is 0.9 nM
技术资料暂无技术资料 索取技术资料
