- ￥326 - 523
- TargetMol
- 美国
- T5499
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
gardiquimod TFA salt
- 库存：
10
- 供应商：
TargetMol
- CAS号：
1159840-61-5
- 规格：
2 mg/5 mg
| 规格： | 2 mg | 产品价格： | ￥326.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥523.0 |
Product Introduction
Bioactivity
英文名:gardiquimod TFA salt
描述:Gardiquimod diTFA, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod diTFA could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod diTFA specifically activates TLR7 when used at concentrations below 10 μM. Gardiquimod diTFA could function as both an immune system modifier and a reverse transcriptase inhibitor as a novel therapeutic agent to block systemic and mucosal transmission of HIV-1.[1] [2].
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文献和实验prior to rehydration with enzyme.After digestion,the peptides are extracted from the gel and mass analyzed.In-gel digestion procedureMaterials25 mM NH4HCO3 in 50% acetonitrile25 mM NH4HCO3,pH 85% TFA/ 50% acetonitrile0.1 mg/ml trypsin (sequence grade,Promega)in 25 mM
In-gel digestion of proteins for peptide fingerprint mapping
4 HCO 3 , pH 8 5% TFA/ 50% acetonitrile 0.1 m g/ m l trypsin (sequence grade, Promega) in 25 mM NH 4 HCO 3 , pH 8 10 mM dithiotreitol in 25 mM NH4 HCO 3 55 mM iodoacetamide in 25 mM NH 4 HCO 3 Generally, trypsin is the protease
Aldrich 233781-10G For TFA cleavage 1,2-Dichloroethane JT Baker JTH076-33
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