- ￥3180 - 10700
- TargetMol
- 美国
- T37488
- 2025年07月02日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
10(S),17(S)-DiHDHA
- 库存：
10
- 供应商：
TargetMol
- CAS号：
871826-47-0
- 规格：
25 μg/100 μg/50 μg
| 规格： | 25 μg | 产品价格： | ￥3180.0 |
|---|---|---|---|
| 规格： | 100 μg | 产品价格： | ￥10700.0 |
| 规格： | 50 μg | 产品价格： | ￥5670.0 |
Product Introduction
Bioactivity
英文名:10(S),17(S)-DiHDHA
描述:Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. 10(S),17(S)-DiHDHA is a DHA metabolite, also referred to as protectin DX (PDX). It is produced by an apparent double lipoxygenase (LO)-mediated reaction in murine peritonitis exudates, in suspensions of human leukocytes, or by soybean 15-LO incubated with DHA. It differs from protectin D1 with respect to the stereochemistry of the C-10 hydroxyl and the double bond configuration at the 13 and 15 positions. 10(S),17(S)-DiHDHA blocks neutrophil infiltration in murine peritonitis by 20-25% at a dose of 1 ng/mouse. It also inhibits platelet activation by both impairing thromboxane (TX) synthesis and TX receptor activation.
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