- ￥8400 - 16700
- TargetMol
- 美国
- T35429
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
AC-4-130
- 库存：
10
- 供应商：
TargetMol
- CAS号：
1834571-82-2
- 规格：
100 mg/50 mg/25 mg
| 规格： | 100 mg | 产品价格： | ￥16700.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥10800.0 |
| 规格： | 25 mg | 产品价格： | ￥8400.0 |
Product Introduction
Bioactivity
英文名:AC-4-130
描述:AC-4-130, a powerful inhibitor of the SH2 domain of STAT5, effectively hinders STAT5 activation, dimerization, nuclear translocation, and transcription of genes reliant on STAT5. This compound directly binds to STAT5, ultimately leading to cell cycle arrest and apoptosis in FLT3-ITD-driven leukemic cells. AC-4-130 exhibits notable anti-cancer properties and effectively suppresses abnormal STAT5 activity in acute myeloid leukemia (AML), making it a promising therapeutic option [1].
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文献和实验Isolation of Sequences Flanking Ac Insertion Sites by Ac Casting
Localizing Ac insertions is a fundamental task in studying Ac -induced mutation and chromosomal rearrangements involving Ac elements. Researchers may sometimes be faced with the situation in which the sequence flanking one side of an Ac /Ds
AC-Electrokinetic Applications in a Biological Setting
Dielectrophoresis is a phenomenon which can be exploited to provide significant quantitative electrophysiological data in a range of biochemical setting, from oncology to drug discovery. This chapter seeks to elucidate those applications
Transposon Tagging with AC/Ds in Arabidopsis
(2 ‐5 ). In Arabidopsis, Actzvator/Dissoclation (AC/ Ds) have been used to isolate recessive loss-of-function mutations (6 —8 ), dommant gain of function mutations (9 ) and to isolate genes based on then patterns of expression (10 ,11 ).
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