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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Cys modifier 1
- 库存:
10
- 供应商:
TargetMol
- CAS号:
2374314-08-4
- 规格:
100 mg/25 mg/50 mg
| 规格: | 100 mg | 产品价格: | ¥17500.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥10600.0 |
| 规格: | 50 mg | 产品价格: | ¥13800.0 |
Product Introduction
Bioactivity
英文名:Cys modifier 1
描述:Cys modifier 1 (compound 7) is a cysteine-selective protein modifier for protein bioconjugation as well as a fluorescent carbonylacrylic derivative bearing nitrobenzofurazan (λ ex =465nm and λ em 539 nm) [1].

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文献和实验32)的X线结晶图像,结果显示它们具有相似的空间结构,在P20的C端和P10的N端有200多个氨基酸残基的序列尤为保守,在空间结构上组成相似的b 折叠中心和相邻的a 螺旋,保守的、对蛋白酶活性有特殊意义的氨基酸残基均位于这一段,并形成特定的结构。不同源的序列主要存在于P20的N端和P20与P10交界处,这两个部位的氨基酸残基在蛋白酶活化过程中一般被全部或部分切除。 所有的成员都保守性地包含有与底物P1Asp作用的氨基酸残基,如在ICE中,它们是催化中心的Cys285
Disulfide Conjugation of Peptides to Oligonucleotides and Their Analogs
1: Conjugation of Peptides with Oligonucleotide Analogs Containing Negatively Charged Phosphates Alternate Protocol 1: Conjugation of C‐Terminal Cys‐Containing Peptides to Oligonucleotides via Activation of the Oligonucleotide
Studies of the Ubiquitin Proteasome System
both in vitro and in cells. Because another protein modifier, NEDD8, itself regulates aspects of the ubiquitin system, basic protocols on neddylation are also included in this unit. Keywords: Ubiquitin; ubiquitylation; proteasomal degradation; protein
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