- ￥1060 - 1790
- TargetMol
- 美国
- T18058
- 2025年10月01日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
K-Ras ligand-Linker Conjugate 5
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2378261-85-7
- 规格：
2 mg/5 mg
| 规格： | 2 mg | 产品价格： | ￥1060.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1790.0 |
Product Introduction
Bioactivity
英文名:K-Ras ligand-Linker Conjugate 5
描述:K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The K-Ras ligand-Linker Conjugate 5 plays a crucial role in the synthesis of PROTAC K-Ras Degrader-1, a highly potent K-Ras degrader. In SW1573 cells, this degrader exhibits an impressive degradation efficacy of ≥70% [1].
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验AntibodyDrug Conjugate (ADC) Clinical Pipeline: A Review
game, requiring thoughtful combination of antibody, linker, and drugs in the context of a target and a defined cancer indication. Lessons learned from the first-generation antibody–drug conjugate (ADC) and improvement of the technology guided the design
In Vivo Testing of Drug-Linker Stability
drug release in circulation and efficiently converted into active drugs in the tumor tissues. Designing the right combination of monoclonal antibody (mAb), linker and drug, requires monitoring and understanding the behavior of all three components
Attachment of Reporter and Conjugate Groups to the 3′ Termini of Oligonucleotides
Figure 4.5.1 Generic oligonucleotide 3′‐conjugate. View Image
技术资料暂无技术资料 索取技术资料
