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文献和实验Identification of Human MHC Class I Binding Peptides using the iTOPIA Epitope Discovery System
CD8+ T cells recognize antigenic peptides presented in the context of MHC class I. They play a key role in cellular immunity and are crucial for longterm protective immunity to many infectious diseases. The quest for new and enhanced vaccines
Molecular Typing of the MHC Class I Chain-Related Gene Locus
The human major histocompatibility complex (MHC) class I chain-related genes A and B (MICA and MICB ) are located within the human leukocyte antigen (HLA) class I region of chromosome 6 (1 ). Their organization, expression, and products
of charge, but for research purpose only (Table 1 ). The construction of MHC class II-peptide tetrameric complexes has proven to be more problematic than class I, with a fewer publications mainly involving mouse tetramers and no standard protocol.
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