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文献和实验Chemokine control of HIV-1 infection
underlying viral entry and tropism 4 . The virus strains responsible for transmission, which are the predominant virus type isolated from asymptomatic HIV-positive individuals, use CCR5 as a receptor, whereas viruses that emerge later in the course
A chemokine-driven positive feedback loop organizes lymphoid follicles
Lymphoid follicles are B-cell-rich compartments of lymphoid organs that function as sites of B-cell antigen encounter and differentiation. CXC chemokine receptor-5 (CXCR5) is required for B-cell migration to splenic
Overview of Receptor Allosterism
Figure 1.21.2 Effect of: (A ) negative allosteric modulator, (B ) positive allosteric modulator, or (C ) a competitive antagonist on orthosteric ligand‐receptor occupancy (ρA ). For all the simulations, p K
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