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文献和实验A Sensitive Assay for the Enzymatic Activity of GTP Cyclohydrolase I
enzyme in the biosynthetic pathway of BH 4 is GTP cyclohydrolase I (EC 3.5.4.16). Cellular expression of this enzyme is subject to varied and multi-level control that is cell-type specific. For example, the activity of GTP cyclohydrolase I in immune cells
Overview of Receptor Allosterism
concentrations of positive or negative modulator. The solid circles on the control saturation‐binding isotherm of [A*] indicate three arbitrarily chosen levels of occupancy (denoted L, I, and H) by the radioligand. The lower two panels (B, C ) illustrate
THE PURINE NUCLEOTIDE CONTENT IN HUMAN LEUKEMIA CELL LINESAbstract: The HPLC method was used to determine the purine nucleotide (ATP, ADP, AMP, GTP, GDP, GMP, NAD+) contents and the values of the adenylate energy charge (AEC) and guanylate energy
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