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文献和实验Assaying Peptide Translocation by the Peptide Transporter TAP
. The peptide transporter TAP translocates peptides over this ER membrane which is critical for successful MHC class I antigen presentation. How peptide translocation by TAP can be assayed and inhibitors of chemical or viral origin can be identified
Transporter Current Measurements
Na+ /K+ pump, Na+ /Ca2+ exchanger, glutamate transporter and other transporters for dopamine, norepinephrine, GABA, and others, are all electrogenic. These transporters or exchanger transport Na+ ions, with or without transmitters
Photolabeling the Transporter Associated with Antigen Processing
in cellular membranes, and the identification of novel peptide-binding proteins (3 -5 ). Crosslinkers function by coupling reactive groups to amino acid side chains of peptides, and are divided into two groups; homobifunctional or heterobifunctional
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