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文献和实验Assembly of Matched Alpha/Beta Subunits to HLA Class II Peptide Receptors
on the same chromosome) or trans (encoded on different chromosomes) combinations. Since some of the α–β combinations may yield mismatched non-functional α–β heterodimers, it is not entirely clear which type of HLA class II peptide receptors are found on the cell surface
of beta-cell autoimmunity in mice. The first protocol describes the detection of insulin-specific autoantibodies using a radio-binding assay. The other is a general CD8+ T cell ELISpot protocol for the detection of peptide-specific responses of CD8+ T
Evaluating Amyloid Beta (A) 1-40 Degradation by Capillary Electrophoresis
Here, we describe a capillary electrophoresis method for evaluating proteolysis of the amyloid beta peptide (Aβ) 1–40. This method is suitable for kinetic studies, demands little specialized equipment, and consumes only small
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