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文献和实验Purification, Quantification, and Functional Analysis of Complement Factor H
fish. Human FH protein concentration can be quantified by sandwich ELISA. The activity of FH is generally measured by assays which detect the cleavage, by complement factor I, of the complement protein C3b to form iC3b. Cleavage occurs
Antibody-Cytokine Fusion Proteins for the Therapy of Cancer
In recent years the development of tumor-specific recombinant antibodies fused to immunostimulatory cytokines such as interleukin-2 (IL-2), interleukin-12 (IL-12), and granulocyte/mac rophage colony-stimulating factor (GM-CSF) has provided
Both botulinum neurotoxins (BoNTs) and anthrax lethal factor, a component of anthrax toxin, exhibit zinc metalloprotease activity. The assay detailed here is capable of quantitatively detecting these proteins by measuring their enzymatic
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