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文献和实验Epitope Mapping Using Homolog-Scanning Mutagenesis
of antibody-binding sites using serial chimeric proteins of different homologs, a technique termed homolog-scanning mutagenesis (HSM), has proven to be especially useful in mapping conformational epitopes.
in cellular proliferation. Indeed, the identification of the involvement of c-mos in meiosis is an excellent example of the manner in which oocytes have proven useful for establishing gene function (1,2) . c-mos is the cellular homolog of the viral mos
populations of cells for subsequent molecular analysis. The polycomb group (PcG) protein, enhancer of zeste homolog 2 (EzH2), a methyl-transferase that plays a key role in �transcriptional gene repression, is frequently overexpressed in several malignant
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