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文献和实验A chemokine-driven positive feedback loop organizes lymphoid follicles
, establishing a positive feedback loop that is likely to be important in follicle development and homeostasis. In germinal centres the feedback loop is overridden, with B-cell lymphotoxin 1 2 expression being induced by a mechanism
Surrogate Markers of Angiogenesis and Metastasis
Angiogenesis, the formation of new blood vessels from a preexisting vascular network, is a complex multistep process under the control of positive and negative factors (bi1 ,bi2 ). Growth, progression, and metastasis of malignant tumors
after specifically interacting with its receptors. Human IL-2 is a 133-amino acid polypeptide with a molecular mass of 15-18 kDa. IL-2 signaling is mediated by a multichain receptor complex consisting of an alpha (CD25), beta (CD122), and gamma (CD132) chain. The IL
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