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TGFβ1/ TGFB1, Mouse, Recombina

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  • ¥2080 - 27980
  • 普诺赛
  • PCK099
  • 国产
  • 2025年07月29日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现货

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10μg/500μg/50μg/1mg

    规格:10μg产品价格:¥2080.0
    规格:500μg产品价格:¥18980.0
    规格:50μg产品价格:¥6180.0
    规格:1mg产品价格:¥27980.0

    产品信息

    别名 TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP;latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1; TGF-β1; TGF beta1; TGFbeta 1; TGF-beta 1; TGFbeta
    物种 Mouse
    表达宿主 Human Cells
    序列信息 Ala279-Ser390
    检索号 P04202
    分子量 12.8 kDa
    表观分子量 13 kDa
    生物活性 Measured by its ability to inhibit IL-4-dependent proliferation of TF‑1 human erythroleukemic cells.The ED50 for this effect is 5-25 pg/ml.

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素 < 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂 Lyophilized from a 0.2 μm filtered solution of 4mM Hcl.
    复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 4mM Hcl.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    Transforming Growth Factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β Receptor type II (TβR-II), and a TGF-β Receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

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