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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Bicuculline
- 供应商:
上海汇谱仪器有限公司
- CAS号:
485-49-4
- 规格:
25mg
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文献和实验[3H]-GABA Binding to GABAA and GABAB Sites on Rat Brain Crude Synaptic Membranes
of antagonism by bicuculline and insensitivity to the GABA-analog baclofen, whereas GABAB receptors are stimulated by baclofen and are insensitive to bicuculline; GABAC receptors are insensitive to both (1 ).
Characterization of GABA Receptors
) (–)‐Bicuculline methiodide (Sigma‐Aldrich, or ICN Biomedicals) Muscimol (unlabeled) γ‐Amino‐n ‐butyric
Saturation Assays of Radioligand Binding to Receptors and Their Allosteric Modulatory Sites
. The binding of ligands (e.g., the agonist muscimol and antagonist bicuculline) to the GABA receptor requires both α and β subunits. Similarly, both α and γ subunits are required for optimal binding of the agonist diazepam and the antagonist flumazenil
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