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NF- κB Reporter (Luc) - THP-1

Cell Line
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  • 询价
  • BPS Bioscience
  • 美国
  • 79645
  • 2025年09月26日
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      Cell line

    • 供应商

      盛祺兆生物

    • 运输方式

      干冰

    • 规格

      2 vials

    The NF-κB reporter (Luc)-THP-1 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

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    图标文献和实验
    相关实验
    • Imaging NF-B Signaling in Mice for Screening Anticancer Drugs

      . Currently, there are various assays available to study NF-κB activation in vitro, however, techniques involving the imaging of NF-κB in vivo models remains limited. Male NF-κB-RE-luc (Oslo) mice from Xenogen Corporation (Alameda, California) provide a great model for studying

    • Cell-Based Reporter Assay to Analyze Activation of Nod1 and Nod2

      pathways. In this chapter, we describe a quick and reliable cell-based assay using a luciferase reporter to measure Nod1- and Nod2-mediated NF-κB activation. The described protocol was successfully applied to analyze the influences of overexpressed proteins

    • How to Monitor NF-B Activation After Photodynamic Therapy

      The nuclear factor-kappa B (NF-κB) is a multipotent factor involved in many cellular processes such as inflammation, immune response and embryonic development and it can be activated by a large number of stimuli. Consequently

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