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- CLOUD-CLONE
- MAA529Hu25
- 2025年07月15日
- WB; IHC
- 小鼠
- Human，人
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
杭州昊鑫生物
- 库存：
100
- 靶点：
TM
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
12个月
- 抗体英文名：
Monoclonal Antibody to Thrombomodulin (TM)
- 抗体名：
TM抗体
- 宿主：
小鼠
- 适应物种：
Human，人
- 亚型：
IgG2a Kappa
- 形态：
液体
- 应用范围：
WB; IHC
- 保存条件：
-20°
- 浓度：
1mg/ml
- 规格：
10ul（仅限杭州终端客户）
血栓调节蛋白(TM)单克隆抗体
Monoclonal Antibody to Thrombomodulin (TM)
CD141; THBD; BDCA3; THRM; Fetomodulin
- 编号MAA529Hu25
- 物种Homo sapiens (Human，人) 相同的名称，不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)H1
- Ig亚型IgG2a Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原RPA529Hu01-血栓调节蛋白(TM)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性状液体
- 浓度1mg/ml
- 且适物种-
- 应用WB; IHC; ICC; IP.
- 下载英文说明书 中文说明书
用法
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
参考文献
| 杂志 | 参考文献 |
| Clin Appl Thromb Hemost. | Is There Any Association Between Thrombosis and Tissue Factor Pathway Inhibitor Levels in Patients With Vitamin D Deficiency? [Pubmed: 24203351] |
| медицинские науки | КЛЕТОЧНО-МОЛЕКУЛЯРНЫЕ МАРКЕРЫ ЭНДОТЕЛИАЛЬНОЙ ДИСФУНКЦИИ И СИСТЕМНОГО ГЕМОСТАЗА ПРИ ВИБРАЦИОННОЙ БОЛЕЗНИ В … [Ru:Source] |
| FASEB J. | Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice [Pubmed:24451386] |
| Gynecol Endocrinol. | The effect of hormone therapy on biochemical and ultrasound parameters associated with atherosclerosis in 46, XY DSD individuals with female phenotype [Pubmed:24911331] |
| Informa Healthcare | Changes in cardiac thrombomodulin and heat shock transcription factor 1 expression and peripheral thrombomodulin and catecholamines during hypothermia in rats [Pubmed:25109347] |
| Bone Marrow Transplant. | Thrombomodulin alleviates murine GVHD in association with an increase in the proportion of regulatory T cells in the spleen [Pubmed:25243628] |
| Biomed Res Int | Basic Fibroblast Growth Factor Ameliorates Endothelial Dysfunction in Radiation-Induced Bladder Injury [PubMed: 26351640] |
| Molecular Nutrition & Food Research | Trans‐fatty acid promotes thrombus formation in mice by aggravating antithrombogenic endothelial functions via Toll‐like receptors [PubMed: 25546502] |
| Acta Biomater | Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: an in vitro osteoblast-osteoclast-endothelial cell co-culture study [PubMed: 26689470] |
| MEDICINE AND EDUCATION IN SIBERIA | КЛЕТОЧНО-МОЛЕКУЛЯРНЫЕ МАРКЕРЫ ЭНДОТЕЛИАЛЬНОЙ ДИСФУНКЦИИ И СИСТЕМНОГО ГЕМОСТАЗА ПРИ ВИБРАЦИОННОЙ БОЛЕЗНИ В СОЧЕТАНИИ С АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИЕЙ [Cozo: Mos] |
| Acta Biomaterialia | Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: An in vitro osteoblast–osteoclast–endothelial cell co-culture study [Pubmed:26689470] |
| Bone Marrow Transplantation | The fifth epidermal growth factor-like region of thrombomodulin exerts cytoprotective functionand prevents SOS in a murine model. [pubmed:27427915] |
| BMC Vet Res. | Blood markers of fibrinolysis and endothelial activation in canine babesiosis. [pubmed:28363279] |
| Haematologica | Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain [Pubmed:29903766] |
| Biomedicine & Pharmacotherapy | Puerarin prevents vascular endothelial injury through suppression of NF-κB activation in LPS-challenged human umbilical vein endothelial cells [Pubmed:29775893] |
| Scientific Reports | Association between Upper-airway Surgery and Ameliorative Risk Markers of endothelial function in obstructive Sleep Apnea [Pubmed: 31882827] |
| Intensive Care Medicine Experimental | Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental … [34169407] |
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文献和实验该产品被引用文献
参考文献
| 杂志 | 参考文献 |
| Clin Appl Thromb Hemost. | Is There Any Association Between Thrombosis and Tissue Factor Pathway Inhibitor Levels in Patients With Vitamin D Deficiency? [Pubmed: 24203351] |
| медицинские науки | КЛЕТОЧНО-МОЛЕКУЛЯРНЫЕ МАРКЕРЫ ЭНДОТЕЛИАЛЬНОЙ ДИСФУНКЦИИ И СИСТЕМНОГО ГЕМОСТАЗА ПРИ ВИБРАЦИОННОЙ БОЛЕЗНИ В … [Ru:Source] |
| FASEB J. | Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice [Pubmed:24451386] |
| Gynecol Endocrinol. | The effect of hormone therapy on biochemical and ultrasound parameters associated with atherosclerosis in 46, XY DSD individuals with female phenotype [Pubmed:24911331] |
| Informa Healthcare | Changes in cardiac thrombomodulin and heat shock transcription factor 1 expression and peripheral thrombomodulin and catecholamines during hypothermia in rats [Pubmed:25109347] |
| Bone Marrow Transplant. | Thrombomodulin alleviates murine GVHD in association with an increase in the proportion of regulatory T cells in the spleen [Pubmed:25243628] |
| Biomed Res Int | Basic Fibroblast Growth Factor Ameliorates Endothelial Dysfunction in Radiation-Induced Bladder Injury [PubMed: 26351640] |
| Molecular Nutrition & Food Research | Trans‐fatty acid promotes thrombus formation in mice by aggravating antithrombogenic endothelial functions via Toll‐like receptors [PubMed: 25546502] |
| Acta Biomater | Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: an in vitro osteoblast-osteoclast-endothelial cell co-culture study [PubMed: 26689470] |
| MEDICINE AND EDUCATION IN SIBERIA | КЛЕТОЧНО-МОЛЕКУЛЯРНЫЕ МАРКЕРЫ ЭНДОТЕЛИАЛЬНОЙ ДИСФУНКЦИИ И СИСТЕМНОГО ГЕМОСТАЗА ПРИ ВИБРАЦИОННОЙ БОЛЕЗНИ В СОЧЕТАНИИ С АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИЕЙ [Cozo: Mos] |
| Acta Biomaterialia | Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: An in vitro osteoblast–osteoclast–endothelial cell co-culture study [Pubmed:26689470] |
| Bone Marrow Transplantation | The fifth epidermal growth factor-like region of thrombomodulin exerts cytoprotective functionand prevents SOS in a murine model. [pubmed:27427915] |
| BMC Vet Res. | Blood markers of fibrinolysis and endothelial activation in canine babesiosis. [pubmed:28363279] |
| Haematologica | Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain [Pubmed:29903766] |
| Biomedicine & Pharmacotherapy | Puerarin prevents vascular endothelial injury through suppression of NF-κB activation in LPS-challenged human umbilical vein endothelial cells [Pubmed:29775893] |
| Scientific Reports | Association between Upper-airway Surgery and Ameliorative Risk Markers of endothelial function in obstructive Sleep Apnea [Pubmed: 31882827] |
| Intensive Care Medicine Experimental | Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental … [34169407] |
相关实验
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人血栓调节蛋白 (TM)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 TM （Thrombomodulin ） 单抗包被于酶标板上，标准品和样品中的 TM与单抗结合，加入
人 血栓调节蛋白 (TM) 酶联免疫分析（ ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中 血栓调节蛋白(TM) 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中人 血栓调节蛋白 (TM) 水平。用纯化的人 血栓调节蛋白 (TM) 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 血栓调节蛋白 (TM) 再与 HRP 标记的 血栓调节蛋白
人 血栓调节蛋白 (TM) 酶联免疫分析（ ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中 血栓调节蛋白(TM) 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中人 血栓调节蛋白 (TM) 水平。用纯化的人 血栓调节蛋白 (TM) 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 血栓调节蛋白 (TM) 再与 HRP 标记的 血栓调节蛋白
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血栓调节蛋白(TM)单克隆抗体
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