Mouse Monoclonal Antibody to CD46

Mouse Monoclonal Antibody to C

D46
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  • ¥1280 - 2180
  • Tanda
  • 中国
  • TD-31495
  • 2025年10月18日
  • FCM、ELISA、IHC
  • Mouse
  • Human
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    • 详细信息
    • 技术资料
    • 免疫原

      peptide

    • 亚型

      IgG1

    • 形态

      Liquid

    • 保存条件

      -20℃

    • 克隆性

      mAb

    • 适应物种

      Human

    • 保质期

      1年

    • 目录编号

      TD-31495

    • 级别

      科研级

    • 库存

      88

    • 供应商

      武汉天德

    • 宿主

      Mouse

    • 应用范围

      FCM、ELISA、IHC

    • 靶点

      详询

    • 抗体英文名

      Mouse Monoclonal Antibody to CD46

    • 抗体名

      CD46

    • 规格

      100ul/50ul

    规格:100ul产品价格:¥2180.0
    规格:50ul产品价格:¥1280.0

    Mouse Monoclonal Antibody to CD46

    Description

    The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

    Specification

    Aliases MCP; TLX; AHUS2; MIC10; TRA2.10
    Entrez GeneID 4179
    Swissprot P15529
    clone 1A5A5
    WB Predicted band size 43.7kDa
    Host/Isotype Mouse IgG1
    Antibody Type Primary antibody
    Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
    Species Reactivity Human
    Immunogen Purified recombinant fragment of human CD46 (AA: extra 35-179) expressed in E. Coli.
    Formulation Purified antibody in PBS with 0.05% sodium azide

    Application

    IHC 1/200 - 1/1000
    FCM 1/200 - 1/400
    ELISA 1/10000

    Product Image

    • Mouse Monoclonal Antibody to C
      Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
    • Mouse Monoclonal Antibody to C
      Flow cytometric analysis of K562 cells using CD46 mouse mAb (green) and negative control (red).
    • Mouse Monoclonal Antibody to C
      Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD46 mouse mAb with DAB staining.
    • Mouse Monoclonal Antibody to C
      Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CD46 mouse mAb with DAB staining.
       

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