Nordoxepin-d4去甲盐酸多塞平-d4,224981

Nordoxepin-d4 hydrochloride 产品活性：Nordoxepin-d4 (Desmethyldoxepin-d4) hydrochloride 是氘代标记的 Nordoxepin (hydrochloride) (HY-100046)。 产品来源： www.medchemexpress.cn/nordoxepin-d4-hydrochloride.html 研究领域：Metabolic Enzyme/Protease | Others 作用靶点：Drug Metabolite | Isotope-Labeled Compounds In Vitro: Stable or radioisotope-labeled compounds allow precise tracking and quantification of individual atoms in metabolic pathways. Stable isotopes generally do not change molecular properties but may slightly affect metabolic kinetics; radioactive isotopes may interfere with cells. Markers can distinguish endogenous and exogenous metabolites, reduce false positives, and are beneficial to quantification and reconstruction of metabolic pathways.In cell culture or enzymatic reactions, the use of isotope markers can precisely control the concentration and exposure time, making it easy to study metabolic reactions and enzyme activities. Through stable isotope analytical metabolomics (SIRM), cellular metabolic networks can be studied, key metabolic nodes and regulatory mechanisms can be identified, and targets can be provided for compound development.Isotope-labeled compounds can be used in competition binding experiments to evaluate the affinity and binding kinetics of compounds to receptors to help optimize design. Stable isotope labels are used as internal standards in mass spectrometry analysis to improve analysis accuracy and reproducibility and reduce matrix effect interference. In Vivo: Isotopic labels can non-invasively track the distribution, transformation and clearance of compounds and their metabolites in the body through techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR), which is beneficial to the study of pharmacometabolic kinetics (ADME).Isotope labeling can reveal specific steps in metabolic pathways. Using compounds with stable isotope labels at specific locations directly in humans or animal models can also help verify drug mechanisms and evaluate unexpected side effects, improving the accuracy and efficiency of clinical research. 相关产品：Clozapine N-oxide | SN-38 | Calcitriol | Urolithin A | Oseltamivir acid | Teriflunomide | Phosphoramide mustard cyclohexanamine | Gemfibrozil 1-O-β-glucuronide | 4-Hydroperoxy cyclophosphamide | Mycophenolate Mofetil | Monomethyl fumarate | VRT-043198 | Penicillamine | Linsidomine hydrochloride | GS-443902 trisodium | MTIC | Pyocyanin | Nortriptyline hydrochloride | 4-Hydroxymephenytoin | L-Lactic acid-13C3 sodium | L-Valine-d8 | Ercalcitriol | Abemaciclib metabolite M2 | Endoxifen hydrochloride | Sodium cyanoboronhydride-d3 | Oxypurinol | 1'-Hydroxymidazolam | 3-Indoleacetic acid-d5 | NAPQI 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种TOP期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪前沿的制药及生命科学研究进展，为您提供全球前沿的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。