无动物成分重组人sCD40 Ligand

无动物成分重组人sCD40 Ligand 英文名称：Animal-Free Recombinant Human sCD40 Ligand 规格：10ug 价格：￥1,395 货号：AF-310-02-10ug 不含动物成分蛋白/ANIMAL-FREE PROTEINS 产品描述： Animal-Free Recombinant Human sCD40 Ligand CD40, a member of the TNF receptor superfamily, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40 Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to “immunodeficiency with hyper-IgM”, a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain. The soluble form of CD40L is an 18 kDa protein comprising the entire TNF homologous region of CD40L and is generated in vivo by an intracellular proteolytic processing of the full length CD40L. Recombinant Human soluble CD40 ligand is a 16.3 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: soluble CD40 Ligand, TNFSF5, TRAP, CD154, Gp39, T-BAM AA Sequence: MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to stimulate the proliferation of HEK-BlueTM CD40 reporter cells. Calculated Molecular Weight: 16.3 kDa Accession Number: P29965 Gene ID: 959 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human无动物成分重组人sCD40 Ligand 齐一生物代理PeproTech的产品原装正品质量、到货快捷、专业的物流配送、专人全程跟踪订单、确保货物安全、准确及时地送达指定地点、欢迎您的来电咨询！ PeproTech重组蛋白与科学服务领域是由经验丰富的蛋白质科学家开发出来的，因此能够为制备抗体提供高品质的原料。重组蛋白到抗原亲和纯化的抗体拥有自己的研发系统，能够保证产品的高品质。 PeproTech的高品质细胞因子生产商，产品包括原核和真核细胞表达的高质量的重组蛋白，PeproGMP®细胞因子，无动物成分细胞因子，生长因子和细胞因子，趋化因子，神经营养因子等，抗原亲和纯化的多克隆抗体，生物素标记的多克隆抗体，单克隆/多克隆抗体，对照抗体，ABTS ELISA试剂盒，TMB ELISA试剂盒，酶联免疫吸附开发试剂盒，相关培养基等。