无动物成分重组人IL-37（IL-1F7）

无动物成分重组人IL-37（IL-1F7） 英文名称：Animal-Free Recombinant Human IL-37 (IL-1F7) 规格：5ug 价格：￥1,402 货号：AF-200-39-5ug 不含动物成分蛋白/ANIMAL-FREE PROTEINS 产品描述： Animal-Free Recombinant Human IL-37 (IL-1F7) The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-37 (IL-1F7), which acts as a modulator of the immune response. Reduction of IL-37 synthesis in PBMCs leads to increased production of proinflammatory cytokines including IL-1 alpha, IL-1 beta, IL-6 and TNF- alpha. The role of IL-37 as an inhibitor of the innate inflammatory response is also corroborated by the observation that it is highly expressed in synovial tissue from patients with rheumatoid arthritis. Full length IL-37 resides primarily in the cytoplasm, but after activation through cleavage by CASP1, it can translocate to the nucleus where it exerts its activity by direct interaction with SMAD3. Recombinant Human IL-37 is a 19.4 kDa protein consisting of 174 amino acids, corresponding to the mature activated form of IL-37. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Interleukin-37, IL-1F7, IL-1ζ (zeta), IL-1H4 AA Sequence: MVHTSPKVKN LNPKKFSIHD QDHKVLVLDS GNLIAVPDKN YIRPEIFFAL ASSLSSASAE KGSPILLGVS KGEFCLYCDK DKGQSHPSLQ LKKEKLMKLA AQKESARRPF IFYRAQVGSW NMLESAAHPG WFICTSCNCN EPVGVTDKFE NRKHIEFSFQ PVCKAEMSPS EVSD Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Measured by its ability to bind Interleukin-18 Binding Protein isoform a (IL-18 BPa) in functional ELISA. Calculated Molecular Weight: 19.4 kDa Accession Number: Q9NZH6 Gene ID: 27178 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)无动物成分重组人IL-37（IL-1F7） 齐一生物代理PeproTech的产品原装正品质量、到货快捷、专业的物流配送、专人全程跟踪订单、确保货物安全、准确及时地送达指定地点、欢迎您的来电咨询！ PeproTech重组蛋白与科学服务领域是由经验丰富的蛋白质科学家开发出来的，因此能够为制备抗体提供高品质的原料。重组蛋白到抗原亲和纯化的抗体拥有自己的研发系统，能够保证产品的高品质。 PeproTech的高品质细胞因子生产商，产品包括原核和真核细胞表达的高质量的重组蛋白，PeproGMP®细胞因子，无动物成分细胞因子，生长因子和细胞因子，趋化因子，神经营养因子等，抗原亲和纯化的多克隆抗体，生物素标记的多克隆抗体，单克隆/多克隆抗体，对照抗体，ABTS ELISA试剂盒，TMB ELISA试剂盒，酶联免疫吸附开发试剂盒，相关培养基等。