重组人VEGF-B

重组人VEGF-B 英文名称：Recombinant Human VEGF-B 规格：5ug 价格：￥1,128 货号：100-20B-5ug RUO PROTEINS VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, helps regulate angiogenesis and vascular permeability, and inhibits apoptosis in certain smooth muscle cells and neurons. VEGF-B is expressed in all tissues except the liver. It forms cell surface-associated, disulfide-linked homodimers, and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a cysteine knot-like structural motif, but differ in their carboxyl-terminal domains. Both VEGF-B isoforms signal only through the VEGFR1 receptor. Recombinant Human VEGF-B is a 38.0 kDa, disulfide-linked homodimeric protein consisting of two 167 amino acid polypeptide chains. Source: E.coli Synonyms: Vascular Endothelial Growth Factor-B, VEGF-related factor, VRF AA Sequence (monomer): PVSQPDAPGH QRKVVSWIDV YTRATCQPRE VVVPLTVELM GTVAKQLVPS CVTVQRCGGC CPDDGLECVP TGQHQVRMQI LMIRYPSSQL GEMSLEEHSQ CECRPKKKDS AVKPDSPRPL CPRCTQHHQR PDPRTCRCRC RRRSFLRCQG RGLELNPDTC RCRKLRR Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) in the presence of human VEGF165. The expected ED50 for this effect is 1.0-2.0 μg/ml. Calculated Molecular Weight: 38 kDa Accession Number: P49765 Gene ID: 7423 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Rat重组人VEGF-B 是齐一生物公司重点推广产品，齐一生物代理PeproTech的产品原装正品质量，我公司有专业的人员进行全程指导，请放心购买、发货时均会附上质检报告单、使用说明书和推荐用法用量、提供正规发票欢迎来电咨询！ PeproTech于1988年创立于美国，Peprotech的产品具有很高的性价比，这些细胞因子应用于生命科学研究；在众多高水平的实验室和研究机构中广泛使用。截至2013年底，已被13,000篇SCI文献引用；取得了细胞因子产品领域居于地位。 PeproTech重组蛋白与科学服务领域是由经验丰富的蛋白质科学家开发出来的，因此能够为制备抗体提供高品质的原料。重组蛋白到抗原亲和纯化的抗体拥有自己的研发系统，能够保证产品的高品质。