- ￥960 - 1600
- Solarbio
- K114147P
- 北京
- 2025年07月15日
- WB IHC
- Rabbit
- Human ; Mouse ; Rat
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- 详细信息
- 技术资料
- 供应商：
北京索莱宝科技有限公司
- 库存：
999
- 靶点：
MAP3K8
- 目录编号：
K114147P
- 克隆性：
多克隆
- 抗体英文名：
Anti-MAP3K8 Polyclonal Antibody
- 抗体名：
AURA2;c COT;Cancer Osaka thyroid oncogene;CCOT;COT;COT proto oncogene serine/threonine protein kinase;EST;ESTF;Ewing sarcoma transformant;FLJ10486;M3K8_HUMAN;MAP3K 8;MAP3K8;MEKK8;Mitogen activated protein kinase kinase kinase 8;Mitogen-activated protein kinase kinase kinase 8;Proto oncogene cCot;Proto-oncogene c-Cot;Serine/threonine protein kinase cot;Serine/threonine-protein kinase cot;TPL 2;TPL-2;TPL2;Tumor progression locus 2;
- 宿主：
Rabbit
- 适应物种：
Human ; Mouse ; Rat
- 免疫原：
A synthetic peptide of human MAP3K8
- 亚型：
IgG
- 形态：
液体
- 应用范围：
WB IHC
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 浓度：
WB 1:2000-5000. IHC 1:25-100.
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.
实验图
Western blot analysis with MAP3K8 antibody diluted at 1:3000;Lane: 293T,HepG2,HMC1,HeLa,U937,A549,THP1,MCF7,K-562,HEL.
Immunohistochemistry of paraffin-embedded human thyroid cancer with MAP3K8 antibody diluted at 1:50.
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