产品封面图

Recombinant Human LR3 IGF-1 Pr

otein
收藏
  • ¥269.90 - 1299.90
  • 阿拉丁已认证
  • 上海
  • rp155967
  • 2025年07月15日
    avatar
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 保存条件

      -20°C储存;避免反复冻融

    • 英文名

      Recombinant Human LR3 IGF-1 Protein

    • 库存

      现货

    • 供应商

      上海阿拉丁生化科技股份有限公司

    • 规格

      rp155967-50μg/rp155967-1mg/rp155967-100μg

    规格:rp155967-50μg产品价格:¥269.9
    规格:rp155967-1mg产品价格:¥1299.9
    规格:rp155967-100μg产品价格:¥379.9

     

    产品名称Recombinant Human LR3 IGF-1 Protein
    别名重组人 LR3 IGF-1 蛋白
    规格或纯度ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE&HPLC)
    产品介绍

    pH值:6.5-7.5
    胰岛素样生长因子-1(IGF-1)是一种分子量为7.6kD的激素,其分子结构与胰岛素类似。IGF-1的主要作用机理是通过与其特异性受体(IGF1R)结合来诱导细胞内的信号传导。IGF-1是AKT信号通路的最有效的激活因子之一,激活AKT信号通路后,刺激细胞生长及增殖,并抑制细胞凋亡。IGF-1 LR3在完整的IGF-1分子的N端添加了13个氨基酸形成83个氨基酸的长链IGF-1,并将IGF-1分子的第3个氨基酸谷氨酸(E)用精氨酸(R)取代,所以称为R3。IGF-1 LR3与未作修饰的IGF-1相比,具有更高的稳定性和生物活性。

    Purity

    ≥95.0% SDS-PAGE&HPLC.

     

    Function

    The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.  

     
    生物活性Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is typically less than 10ng/mL.
    内毒素水平<20 EU/mg
    表达系统E.coli
    种属Human
    氨基酸40-118 aa
    序列MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYG SSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA
    纯度≥95%(SDS-PAGE&HPLC)
    蛋白标签No tag
    蛋白长度Full length protein
    无载体Yes
    无动物源Yes
    Accession #P05019.2
    来源重组表达
    预测分子量9.1 kDa
    SDS-PAGE10.1 kDa, under reducing conditions; 10.1 kDa, under non-reducing conditions.

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    • 作者
    • 内容
    • 询问日期
    图标文献和实验
    相关实验
    • Methods for Producing Recombinant Human Cellular Retinaldehyde-Binding Protein

      The cellular retinaldehyde-binding protein (CRALBP) is expressed at high levels in vertebrate visual trssue, where it may serve to modulate the interaction of 11-cis -retinol with visual-cycle enzymes in the retinal pigment epithelium (RPE

    • Recombinant Protein Production in Yeasts

      Recombinant protein production is a multibillion-dollar market. The development of a new product begins with the choice of a production host. While one single perfect host for every protein does not exist, several expression systems ranging

    • Recombinant Protein Expression in Nicotiana

      Recombinant protein pharmaceuticals are now widely used in treatment of chronic diseases, and several recombinant protein subunit vaccines are approved for human and veterinary use. With growing demand for complex protein pharmaceuticals

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ¥5560
    上海万生昊天生物技术有限公司
    2026年01月04日询价
    ¥70
    上海经科化学科技有限公司
    2025年12月10日询价
    ¥1838
    翌圣生物科技(上海)股份有限公司
    2025年11月20日询价
    Recombinant Human LR3 IGF-1 Protein
    ¥269.90 - 1299.90