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- 详细信息
- 技术资料
- 英文名:
6,7-Dimethoxycoumarin
- 库存:
现货
- 供应商:
上海阿拉丁生化科技股份有限公司
- CAS号:
120-08-1
- 规格:
D101245-20mg/D101245-10mg
| 规格: | D101245-20mg | 产品价格: | ¥828.9 |
|---|---|---|---|
| 规格: | D101245-10mg | 产品价格: | ¥535.9 |
Scoparone is a compound found in the herb, Yin Chin, that can up-regulate the expression and activate the CAR (constitutive androstane receptor) found in the liver. It has been shown to clear the accumulation of bilirubin by the activation of CAR in neonatal jaundice. Other studies show that scaparone inhibits lipopolysaccharide (LPS)-induced tissue factor (TF) expression in HUVECs and that it acts as an anti-inflammatory compound. TCPOBOP also transactivates CAR, however, scoparone can activate murine and human CAR. Scaparone can increase dopamine release by synapsin I phosphorylation throμgh activation of PKA and CaMKII? in PC12 cells. It can also activate neurite outgrowth and improve dopamine biosynthesis in PC12 cells.An agent that can up-regulate the expression and activate CAR
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