- ￥161.90 - 4149.90
- 阿拉丁
- 上海
- I111268
- 2025年07月15日
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- 详细信息
- 技术资料
- 保存条件：
2-8°C储存
- 英文名：
Indirubin
- 库存：
现货
- 供应商：
上海阿拉丁生化科技股份有限公司
- CAS号：
479-41-4
- 规格：
I111268-50mg/I111268-250mg/I111268-1g/I111268-10mg
| 规格： | I111268-50mg | 产品价格： | ￥538.9 |
|---|---|---|---|
| 规格： | I111268-250mg | 产品价格： | ￥1838.9 |
| 规格： | I111268-1g | 产品价格： | ￥4149.9 |
| 规格： | I111268-10mg | 产品价格： | ￥161.9 |
Indirubin, also known as isoindigotin, is an inhibitor of cyclin-dependent kinases (CDK1/cyclin B (IC50 = 10μM), CDK2/cyclin A (IC50 = 2.2μM), CDK2/cyclin E (IC50 = 7.5μM), CDK4/cyclin D1 (IC50 = 12μM), CDK5/p35 (IC50 = 5.5μM)) and of GSK-3β (IC50 = 600nM). Studies investigating functional isoindigos show that they have the ability to disrupt cell growth and proliferation. The compound is a potent aryl hydrocarbon receptor ligand and is found in human urine and fetal bovine serum. Synthesized isoindigo-based oligothiophenes are used to study heterojunction solar cells. Shown to inhibit allergic contact dermatitis by regulating T helper mediated immune system in a DNCB-induced model. An inhibitor of GSK-3β and cyclin-dependent kinases.
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