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- 文献和实验
- 技术资料
- 抗体名:
Mouse PD-L1 Antibody 抗体
- 抗体英文名:
Mouse PD-L1 Antibody
- 靶点:
PD-1/PD-L1
- 浓度:
13.27 mg/mL
- 保质期:
12 months from date of receipt.
- 抗原来源:
详询
- 目录编号:
orb2278756
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
Monoclonal
- 保存条件:
详询
- 免疫原:
详询
- 规格:
1 mg/5 mg/10 mg/25 mg
| 规格: | 1 mg | 产品价格: | ¥1287.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥3276.0 |
| 规格: | 10 mg | 产品价格: | ¥5499.0 |
| 规格: | 25 mg | 产品价格: | ¥9828.0 |
产品子类型: Inhibitor Antibody
描述: This monoclonal antibody of the IgG class specifically targets mouse PD-L1 (CD274). It is a well-established tool for blocking the PD-1/PD-L1 pathway, widely used in both in vitro assays and in vivo mouse models for cancer immunotherapy and immune checkpoint research.
克隆号: B32HX1I4
别名: PD1, PD-1, PD1/PDL1, PDL1, PD-L1
分子量: 150 kDa
纯度: >95.0% (May vary between batches)
研究领域: Cell Biology, Immunology & Inflammation
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.
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文献和实验「神药」再显威!杨黄浩等让二甲双胍扮演 PD-L1 「单抗」角色,提高治疗效果
以 PD-1/PD-L1 为代表的免疫检查点抑制剂(Immune Checkpoint Blockades, ICBs)在实体瘤中「大杀四方」,取得了传统治疗方法未有的良好疗效,逐渐成为了继手术、放疗、化疗、靶向治疗后又一种重要的肿瘤治疗手段。然而,免疫检查点抑制剂在实体瘤中的总体有效率依然仅有 20-30%。目前的 PD-1/PD-L1 等抗体类药物治疗依然存在着一些不可避免的问题, 如致命的免疫相关不良事件 (irAE)、复杂的生产工艺、高昂的成本等。此外,基于抗体的 ICBs 通过构象
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