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- 文献和实验
- 技术资料
- 保存条件:
详询
- 保质期:
12 months from date of receipt.
- 英文名:
5-HT2A receptor agonist-3
- 库存:
99
- 供应商:
Biorbyt
- CAS号:
1391499-52-7
- 规格:
25 mg/50 mg/100 mg
| 规格: | 25 mg | 产品价格: | ¥29952.0 |
|---|---|---|---|
| 规格: | 50 mg | 产品价格: | ¥36504.0 |
| 规格: | 100 mg | 产品价格: | ¥44928.0 |
描述: This compound is a highly selective 5-HT2A receptor agonist with a Ki of 2.5 nM and 124-fold selectivity over 5-HT2C. It is a valuable research tool for investigating serotonin receptor function in neuropharmacology, suitable for both in vitro binding assays and in vivo behavioral studies.
靶点: 5-HT Receptor
分子式: C21H26BrNO3
分子量: 420.34
SMILES: O(C)C1=C(C=CC=C1)[C@H]2N[C@H](CC3=C(OC)C=C(Br)C(OC)=C3)CCC2
研究领域: Neuroscience, Pharmacology & Drug Discovery
保存条件: -20°C
备注: For research use only.
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文献和实验Serotonin (5-hydroxytryptamine, 5-HT), was discovered as a serum factor that exerts tonic effects on blood vessels; its chemical structure was elucidated in 1948. The compound gained wide interest among pharmacologists, and in a short time
Distribution of 2A- and 2C-Adrenergic Receptor Immunoreactivity in the Central Nervous System
in the regulation of analgesia, memory, and central cardiovascular control (1 ). Three subtypes of the receptor have been identified (α2A -, α2B -, and α2C -ARs; for review, see ref. 2 ). Comparisons of the three subtypes show a high degree of sequence similarity
Radioligand Binding to Solubilized 5-HT3 Receptors
Most receptors, apart from those for steroid and thyroid hormones, are transmembrane glycoproteins and are generally expressed by tissues in relatively low quantities. Exceptions include the nicotinic acetylcholine receptor in Torpedo
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