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- 文献和实验
- 技术资料
- 保存条件:
详询
- 保质期:
12 months from date of receipt.
- 英文名:
5-HT2C agonist-3 free base
- 库存:
99
- 供应商:
Biorbyt
- CAS号:
2104810-17-3
- 规格:
50 mg/5 mg
| 规格: | 50 mg | 产品价格: | ¥0.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥0.0 |
描述: This small molecule is a potent and selective 5-HT2C receptor agonist (EC50 = 24 nM, Ki = 78 nM). It demonstrates antipsychotic-like properties in vivo by attenuating amphetamine-induced hyperactivity, making it a valuable research tool for neuropsychiatric disorder studies.
靶点: 5-HT Receptor
分子式: C19H22FNO2
分子量: 315.38
SMILES: C(NCC1=C(OC)C=CC=C1)[C@@H]2[C@H](C2)C3=C(OC)C=CC(F)=C3
研究领域: Neuroscience, Pharmacology & Drug Discovery
保存条件: -20°C
备注: For research use only.
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文献和实验2+ ] (1 ,2 ). Later it was observed that high-affinity dyes such as fluo-3 and fura-2, normally saturated in the high-[Ca2+ ] environment of the agonist-sensitive Ca2+ store, could register [Ca2+ ] changes in this compartment under special conditions (e.g., when pools
Free Energy Calculations Applied to Membrane Proteins
Selected applications of free energy calculations to the realm of membrane proteins are reviewed. The theoretical underpinnings of these calculations are described, focusing on free energy perturbation and the use of thermodynamic integration
preparations, GTP can be substituted by 35 S-labeled guanosine 5′-O -(3-thio)triphosphate ([35 S]GTγS) and on agonist stimulation a stable [35 S]GTPγS-Gα complex will form and accumulate. Separation of 35 S-bound GTPγS-Gα complexes from free [35 S]GTPγS allows
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