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详询
- 保质期:
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- 英文名:
HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
- 库存:
99
- 供应商:
Biorbyt
- 规格:
100 μg/1 mg
| 规格: | 100 μg | 产品价格: | ¥0.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥0.0 |
产品名:HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
货号:orb2276739
产品中文名:HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
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文献和实验Science:直击肿瘤命门,Shibin Zhou 等开发靶向 TP53 突变的双特异性抗体
-targeted immunotherapyEurekAlert Science NewsR175H,其中 175 位的精氨酸被组氨酸取代,是 TP53 中观察到的最常见的突变,也是任何肿瘤抑制基因中最常见的突变。HMTEVVRHC (带下划线的为突变氨基酸) 来源于 p53R175H,与人类白细胞抗原 (HLA) 等位基因 (A*02:01) 结合,该等位基因存在于超过 40% 的美国高加索人中。近年来,TCR-Mimic (TCRm) 抗体已成为一类靶向肿瘤细胞内蛋白 pHLA(多肽 - MHC 复合
【分享】Human press METHODS IN MOLECULAR BIOLOGY
Methods and Protocols. Edited by Hofker, Marten H. 2002 210.MHC Protocols Edited by Powis, Stephen H 2002 211.Protein Sequencing Protocols 2nd. Edited by Smith, Bryan John 2002 212.Single Nucleotide Polymorphisms Methods and Protocols Edited by Kwok
α response, we used two human-tumor-derived cell lines: the melanoma line ME-15 (10 ) and the hepatoma line HuH7 (11 ). We have chosen these cell lines as models, because we have a good understanding of the IFNα responses at the mRNA and the protein levels
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