Trimegestone-13C,d3

Trimegestone-13C,d3 产品活性：Trimegestone-13C,d3 是 13C 和氘代标记的 Trimegestone (HY-106827)。Trimegestone (RU 27987) 是一种具有口服活性的去甲孕酮孕激素。Trimegestone 与孕酮受体 (PR) 结合，IC50 值为 3.3 nM (大鼠 PR)。Trimegestone 还增加碱性磷酸酶活性 (EC50=0.1 nM)，但不增加荧光素酶活性。Trimegestone 还表现出弱的抗雄激素活性 (弱雄激素受体亲和力)。Trimegestone 可用于避孕药或更年期综合征的研究。 产品来源： www.medchemexpress.cn/trimegestone-13c-d3.html 研究领域：Vitamin D Related/Nuclear Receptor | Metabolic Enzyme/Protease | Others 作用靶点：Androgen Receptor | Progesterone Receptor | Phosphatase | Isotope-Labeled Compounds In Vitro: Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. 相关产品：Cyclosporin A | Enzalutamide | Tacrolimus | DHEA | Mifepristone | Progesterone | SHP099 | Bavdegalutamide | Calyculin A | β-Glycerophosphate disodium salt pentahydrate | Okadaic acid | Salubrinal | Sodium orthovanadate | Medroxyprogesterone acetate | Ebselen | Batoprotafib | L-Ascorbic acid 2-phosphate trisodium | Apalutamide | Darolutamide | Suramin sodium salt | Osunprotafib | RMC-4550 | Bicalutamide | Spironolactone | TPI-1 | Flutamide | GSK 2830371 | Sodium metatungstate | DT-061