PD-1/PD-L1-IN-43

PD-1/PD-L1-IN-43 产品活性：PD-1/PD-L1-IN-43 (化合物 Z13) 是一种 PD-1/PD-L1 相互作用的小分子靶向抑制剂。PD-1/PD-L1-IN-43 对 B16-F10 黑色素瘤具有较强的体内抗肿瘤作用。PD-1/PD-L1-IN-43 通过阻断 PD-1 和 PD-L1 的相互作用抑制肿瘤生长。PD-1/PD-L1-IN-43 可用于抗肿瘤研究。 产品来源： www.medchemexpress.cn/pd-1-pd-l1-in-43.html 研究领域：Immunology/Inflammation 作用靶点：PD-1/PD-L1 In Vitro: PD-1/PD-L1-IN-43 (0 - 20 μM; 48 h) can reactivate immunosuppressed Jurkat T cells to kill HepG2 cells in the cell co-culture system. In Vivo: PD-1/PD-L1-IN-43 (20 and 40 mg/kg; i.p.; everday for 2 weeks) inhibits potently tumor growth in vivo by activating the tumor immune microenvironment in C57BL/6J male mice. 相关产品：Atezolizumab | Pembrolizumab | Cilengitide | Nivolumab | BMS-1 | BMS-202 | Anti-Mouse PD-1 Antibody (RMP1-14) | JQ-1 (carboxylic acid) | Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) | Durvalumab | Tomivosertib | Avelumab | Pembrolizumab (anti-PD-1) | Sulindac | CA-170 | Camrelizumab | Tislelizumab | BMS-1166 | INCB086550 | BMS-8 | Peresolimab | Fraxinellone | PD-1/PD-L1-IN-9 | Sintilimab | Toripalimab | Rosnilimab | WL12 | Evixapodlin | PROTAC PD-1/PD-L1 degrader-1