- ￥500 - 3200
- 卡梅德/KMD Bioscience
- YR1157
- 天津市
- 2025年08月13日
- FuncS, IF, Neut, ELISA, FCM, IP, ICC
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
Anti-Human CD4 D3 Domain Recombinant Antibody
- 靶点：
CD4 D3 domain[Homo sapiens]
- 浓度：
1mg/ml
- 应用范围：
FuncS, IF, Neut, ELISA, FCM, IP, ICC
- 保质期：
一年
- 抗原来源：
体外表达
- 级别：
科研使用
- 库存：
999
- 供应商：
卡梅德生物科技（天津）有限公司
- 克隆性：
Monoclonal
- 保存条件：
It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
- 形态：
液体/冻干粉
- 亚型：
IgG4 Kappa
- 规格：
100ug/1mg
| 规格： | 100ug | 产品价格： | ￥500.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥3200.0 |
产品编号：YR1157
产品名称：Anti-Human CD4 D3 Domain Recombinant Antibody
分子名称：Ibalizumab
产品别称：科研级 Ibalizumab ( 伊巴组单抗 ), Anti-CD4 D3 Domain Recombinant Antibody, Research Grade Ibalizumab
CAS号：680188-33-4
靶点：CD4 D3 domain[Homo sapiens]
抗体亚型：IgG4 Kappa
克隆性：Monoclonal
宿主：Mouse
来源：CHO Cells
规格：100ug, 200ug, 1mg, 5mg, 10-100mg定制包装
浓度：1mg/ml
纯度：>95% as determined by SDS-PAGE
产品应用：FuncS, IF, Neut, ELISA, FCM, IP, ICC
缓冲体系：PBS, pH7.5
产品背景：Ibalizumab (trade name Trogarzo) is a non-immunosuppressive humanised monoclonal antibody that binds CD4, the primary receptor for HIV, and inhibits HIV from entering cells. It is a post-attachment inhibitor, blocking HIV from binding to the CCR5 and CXCR4 co-receptors after HIV binds to the CD4 receptor on the surface of a CD4 cell.
保存条件：It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
运输条件：Shipped on ice packs.
Note：仅供科研使用
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文献和实验白细胞分化抗原及其功能 CD4 CD4分子为单链跨膜糖蛋白，胞膜外区共有4个IgSF结构域，其中D1、D3为V样区，D2、D4为C2样区。胞质区3个丝氨酸残基(Ser408、Ser415和Ser431)可能是蛋白激酶PKC底物。CD4分子胞质区CXCP基序是与PTKp56lek结合的部位。 小鼠CD4分子常称为L3T4。在外周血和外周淋巴器官中，CD4+T细胞为辅助性T细胞，包括Thl和Th2亚群，以及调节性T细胞(Treg
Intracellular Cytokine Staining Protocol
are first activated in vitro, stained for surface antigens, as in the regular staining protocol, then fixed and permeabilized to allow for anti-cytokine antibodies to stain intracellularly. In vitro stimulation of cells is usually required for detection of cytokines
Intracellular Immunofluorescent Staining for Flow Cytometry
PBMCs were stimulated with TPA/ionomycin in the presence of monensin for 5 hours. The cells were fixed and permeabilized and intracellularly stained with anti-human CD4, clone RPA-T4, (Cat. No. 17-0049 ) and Alexa Fluor® 488 anti-human IL-17 (Cat. No. 53
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