Human RSPO3(C18C)
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Human RSPO3(C18C)

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  • ¥770 - 16200
  • SinoBio
  • 国产
  • C18C
  • 2025年11月08日
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    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Gln22-Val146

    • 保质期

      See instructions

    • 英文名

      标签:C-6His

    • 库存

      表达系统:Human cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥770.0
    规格:50ug产品价格:¥2300.0
    规格:500ug产品价格:¥10800.0
    规格:1mg产品价格:¥16200.0
    产品描述
    Recombinant Human R-Spondin 3 is produced by our Mammalian expression system and the target gene encoding Gln22-Val146 is expressed with a 6His tag at the C-terminus.
    蛋白编号
    Q9BXY4
    产品别称
    R-spondin-3; RSPO3; Protein with TSP type-1 repeat; Roof plate-specific spondin-3; Thrombospondin type-1 domain-containing protein 2; PWTSR; THSD2; CRISTIN1
    偶联
    Unconjugated
    分子量
    14.7 kDa
    表观分子量
    15-25 kDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    纯度-SEC-HPLC
    Greater than 93% as determined by SEC-HPLC.(QC verified)
    生物活性-Cell Based Assay
    Human breast cancer organoids were cultured with Wnt3a (Cat#C22R), Noggin (Cat#CB89) , R-spondin 3 (Cat#C18C) , KGF(Cat#CH73), FGF-10 (Cat#CR11), EGF (Cat#C029) and NRG1-beta 1 (Cat#753). The organoids showed good morphology.
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    R-spondin-3 (RSPO3), also known as Protein with TSP type-1 repeat, Roof plate-specific spondin-3, Thrombospondin type-1 domain-containing protein 2, PWTSR, THSD2 and CRISTIN1, is a member of the thrombospondin type 1 repeat supergene family. RSPO3 is a secreted protein and widely expressed in many tissues. RSPO3 contains two Furin-like repeats which have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases, and one TSP type-1 domain, RSPO3 founctions as a activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Otherwise, RSPO3 may negatively regulate the TGF-beta pathway.

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    图标文献和实验
    该产品被引用文献

    R-spondin-3 (RSPO3), also known as Protein with TSP type-1 repeat, Roof plate-specific spondin-3, Thrombospondin type-1 domain-containing protein 2, PWTSR, THSD2 and CRISTIN1, is a member of the thrombospondin type 1 repeat supergene family. RSPO3 is a secreted protein and widely expressed in many tissues. RSPO3 contains two Furin-like repeats which have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases, and one TSP type-1 domain, RSPO3 founctions as a activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Otherwise, RSPO3 may negatively regulate the TGF-beta pathway.

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    文献支持
    Human RSPO3(C18C)
    ¥770 - 16200