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Human Serpin E2

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  • ¥1200 - 19200
  • SinoBio
  • 国产
  • C961
  • 2026年04月21日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Ser20-Pro397

    • 保质期

      See instructions

    • 英文名

      标签:C-6His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1200.0
    规格:50ug产品价格:¥3520.0
    规格:500ug产品价格:¥13440.0
    规格:1mg产品价格:¥19200.0
    产品描述
    Recombinant Human Glia-derived Nexin is produced by our Mammalian expression system and the target gene encoding Ser20-Pro397 is expressed with a 6His tag at the C-terminus.
    蛋白编号
    P07093-2
    产品别称
    Glia-derived Nexin; GDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; Serpin E2; SERPINE2; PI7; PN1
    偶联
    Unconjugated
    分子量
    42.7 KDa
    表观分子量
    50 KDa, reducing conditions
    剂型描述
    Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    运输条件
    • The product is shipped on dry ice/polar packs.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.
    产品背景
    Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal pancreas and chronic pancreatitis tissue. In contrast, it was strongly over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples. Serpin E2 promotes neurite extension by inhibiting thrombin. It also can bind heparin. It has been shown that Serpin E2 is a novel target of ERK signaling involved in human colorectal tumorigenesis. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.

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    图标文献和实验
    该产品被引用文献

    Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal pancreas and chronic pancreatitis tissue. In contrast, it was strongly over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples. Serpin E2 promotes neurite extension by inhibiting thrombin. It also can bind heparin. It has been shown that Serpin E2 is a novel target of ERK signaling involved in human colorectal tumorigenesis. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.

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    文献支持
    Human Serpin E2
    ¥1200 - 19200