- ￥1200 - 19200
- SinoBio
- 国产
- CP07
- 2025年10月28日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
蛋白表达区间:Met1-Pro407
- 保质期：
See instructions
- 英文名：
标签:N-6His
- 库存：
表达系统:E.coli
- 供应商：
上海经科化学科技有限公司
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥1200.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥3520.0 |
| 规格： | 500ug | 产品价格： | ￥13440.0 |
| 规格： | 1mg | 产品价格： | ￥19200.0 |
- The product is shipped on dry ice/polar packs.
- Upon receipt, store it immediately at the temperature listed below.
- Store at ≤-70°C, stable for 6 months after receipt.
- Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
- Please minimize freeze-thaw cycles.
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文献和实验Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression.
技术资料