Human OLFM4
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Human OLFM4

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  • ¥1200 - 19200
  • SinoBio
  • 国产
  • CS01
  • 2025年10月27日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Asp21-Gln510

    • 保质期

      See instructions

    • 英文名

      标签:C-10His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1200.0
    规格:50ug产品价格:¥3520.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥19200.0
    产品描述
    Recombinant Human Olfactomedin-4 is produced by our Mammalian expression system and the target gene encoding Asp21-Gln510 is expressed with a 10His tag at the C-terminus.
    蛋白编号
    Q6UX06
    产品别称
    Olfactomedin-4; OLM4; Antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; hGC-1; hOLfD; OLFM4; GW112
    偶联
    Unconjugated
    分子量
    56.9 KDa
    表观分子量
    60-90 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, 5%Trehalose, PH7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    Olfactomedin-4/OLFM4 is a secreted protein which contains one olfactomedin-like domain. OLFM4 is expressed during myeloid lineage development,it strongly expressed in the prostate,small intestine,colon and moderately expressed in the bone marrow and stomach. OLFM4 is an antiapoptotic factor that promotes tumor growth. It expressed at high levels in stomach cancer and colon cancer tissues. it promotes proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, OLFM4 inhibits cell growth and induces cell differentiation and apoptosis. Through interaction with cell surface lectins and cadherin, OLFM4 facilitates cell adhesion. It may play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Induction of OLFM4 in cancer cells was reported to have a novel antiapoptotic action via binding to the potent apoptosis inducer GRIM-19.

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    图标文献和实验
    该产品被引用文献

    Olfactomedin-4/OLFM4 is a secreted protein which contains one olfactomedin-like domain. OLFM4 is expressed during myeloid lineage development,it strongly expressed in the prostate,small intestine,colon and moderately expressed in the bone marrow and stomach. OLFM4 is an antiapoptotic factor that promotes tumor growth. It expressed at high levels in stomach cancer and colon cancer tissues. it promotes proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, OLFM4 inhibits cell growth and induces cell differentiation and apoptosis. Through interaction with cell surface lectins and cadherin, OLFM4 facilitates cell adhesion. It may play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Induction of OLFM4 in cancer cells was reported to have a novel antiapoptotic action via binding to the potent apoptosis inducer GRIM-19.

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    文献支持
    Human OLFM4
    ¥1200 - 19200