相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
蛋白表达区间:Ser23-Leu442
- 保质期:
See instructions
- 英文名:
标签:C-6His
- 库存:
表达系统:Human Cells
- 供应商:
上海经科化学科技有限公司
- 规格:
10ug/50ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥1200.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥3520.0 |
| 规格: | 500ug | 产品价格: | ¥12320.0 |
| 规格: | 1mg | 产品价格: | ¥17600.0 |
- Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
- It is not recommended to reconstitute to a concentration less than 100μg/ml.
- Dissolve the lyophilized protein in distilled water.
- Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- The product is shipped at ambient temperature.
- Upon receipt, store it immediately at the temperature listed below.
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
- Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
- Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Lymphocyte-activation gene 3 (LAG3), also known as CD223, is a type I transmembrane protein with four extracellular Ig-like domains, designated D1 to D4 and belongs to the immunoglobulin superfamily. The gene for LAG3 lies adjacent to the gene for CD4 on human chromosome 12p13.32 and shares approximately 20% identical to the CD4 gene. LAG3 is expressed on activated T cells, natural killer cells, B cells and plasmacytoid dendritic cells. LAG3 binds with high affinity to MHC class II molecules, and it interferes competitively with the binding of CD4 to MHC class II and thereby blocks the transduction of stimulatory signals mediated by this interaction. LAG3 negatively regulates cellular proliferation, activation, and homeostasis of T cells, and plays an important role in Treg suppressive function. LAG3 is the target of various drug development programs to develop new treatments for cancer and autoimmune disorders. The soluble form, sLAG-3, is being developed as a cancer drug.
指细胞自移植于新培养基时起,至开始出现活跃繁殖的这一期间。一般被移植的细胞越是培养后期的,其停滞期越长。其原因是培养后期的细胞群在一定程度上进行同步化,而 G1 期的细胞比例高,进入分裂期需要时间;另外来自原培养期间所受的退行性变化的恢复也是重要的原因。
在突变发生的时候,由于细胞含有几个核(或是DNA的双链中只有一条链发生变化),所以要等细胞分裂几次以后,待一个细胞中的所有核(或DNA 的二条链)都是突变的核(或二条链都是突变链)的细胞分离出来的时候,突变性状才能表现出来,这种现象称为分离性迟延现象(如隐性突变的诱发)。
新获得的性状延迟表现的现象。一般诱变剂处理后所发生的突变需要经过好几个世代才能表现出细胞性状的变化。其原因可能有以下几种:( 1)基因虽然发生了突变,但在突变前所产生的物质未被耗尽之前细胞不会表现出突变的性状(例如大肠杆菌中从野生型变成甲硫氨酸缺陷型这种突变)。( 2)诱变剂本身并不是直接作用于 DNA,而是通过一系列的变化之后才能成为真正的诱变剂。( 3)诱变剂引起的 DNA的变化以及相应的突变确定( mutation fixation)是不同的两个过程
技术资料







