产品封面图
文献支持

Human PRL(CM10)

收藏
  • ¥720 - 12800
  • SinoBio
  • 国产
  • CM10
  • 2025年12月22日
    avatar
  • 企业认证

    点击 QQ 联系

  • 万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Leu29-Cys227

    • 保质期

      See instructions

    • 英文名

      标签:C-6His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥720.0
    规格:50ug产品价格:¥2000.0
    规格:500ug产品价格:¥8960.0
    规格:1mg产品价格:¥12800.0
    产品描述
    Recombinant Human Prolactin is produced by our Mammalian expression system and the target gene encoding Leu29-Cys227 is expressed with a 6His tag at the C-terminus.
    蛋白编号
    P01236
    产品别称
    Prolactin; PRL;
    偶联
    Unconjugated
    分子量
    23.9 KDa
    表观分子量
    25-30 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween80, pH 7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    纯度-SEC-HPLC
    Greater than 95% as determined by SEC-HPLC. (Regularly tested)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Non-glycosylated prolactin is produced by the pituitary and packaged in storage granules before secretion, while glycosylated prolactin is reported to be constitutively secreted, have lower biological potency, and be removed from the circulation more quickly. Prolactin is synthesized mainly by the anterior pituitary in all mammals, where secretion is under tonic inhibition by hypothalamic dopamine. In humans, prolactin is also produced peripherally. Prolactin expression is low during early human pregnancy, but increases in late pregnancy. The prolactin receptor (PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. prolactin molecule is thought to bind two receptor molecules. In addition to its lactogenic activity, peripherally produced prolactin plays roles in breast and prostate cancer development, regulation of reproductive function, and immunoregulation.

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献

    Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Non-glycosylated prolactin is produced by the pituitary and packaged in storage granules before secretion, while glycosylated prolactin is reported to be constitutively secreted, have lower biological potency, and be removed from the circulation more quickly. Prolactin is synthesized mainly by the anterior pituitary in all mammals, where secretion is under tonic inhibition by hypothalamic dopamine. In humans, prolactin is also produced peripherally. Prolactin expression is low during early human pregnancy, but increases in late pregnancy. The prolactin receptor (PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. prolactin molecule is thought to bind two receptor molecules. In addition to its lactogenic activity, peripherally produced prolactin plays roles in breast and prostate cancer development, regulation of reproductive function, and immunoregulation.

    相关实验
    • Detection of a Lipid-Lysine Adduct Family with an Amide Bond as the Linkage: Novel Markers for Lipid-Derived Protein Modifications

      kit using the monoclonal antibody to HEL is now commercially available. We recently identified propanoyl-lysine (propionyl-lysine, PRL) from the reaction of an n-3 FA and a lysine residue. The antibody to PRL has been prepared and characterized. Using

    • 类器官培养与应用——垂体瘤类器官

      人垂体肿瘤(human pituitary tumors, HPA)起源于垂体前叶的内分泌细胞,约占所有颅内肿瘤的 15%,通常被认为是良性肿瘤。然而在手术治疗中发现,30-40% 病例发生了局部的侵袭性行为【1】。垂体瘤分为功能性垂体瘤和无功能性垂体瘤,根据瘤细胞分泌的激素将功能性垂体瘤再进一步分为:泌乳素细胞腺瘤(PRL),生长激素细胞腺瘤(GH),促肾上腺皮质激素细胞瘤(ACTH),促甲状腺素细胞瘤(TSH),促性腺激素细胞瘤(LH/FSH)及混合瘤和未分类腺瘤。 目前,侵袭性垂体

    • 腺垂体

      、ACTH、FSH与LH均有各自的靶腺,分别形成:①下丘脑-垂体-甲状腺轴;②下丘脑-垂体-肾上腺皮质轴;③下丘脑-垂体-性腺轴。腺垂体的这些激素是通过调节靶腺的活动而发挥作用的,而GH、PRL与MSH则不通过靶腺,分别直接调节个体生长、乳腺发育与泌乳、黑素细胞活动等。所以,腺垂体激素的作用极为广泛而复杂。 (一)生长素 人生长素(human growth hormone,hGH)含有191个氨基酸,分子量为22000,其化学结构与会催乳素近似,故生长素有弱催乳素作用,而催乳素有弱生长

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ¥2300
    杭州斯达特生物科技有限公司
    2025年10月25日询价
    ¥760
    上海经科化学科技有限公司
    2025年11月06日询价
    ¥1960
    上海羽哚生物科技有限公司
    2025年07月11日询价
    ¥1
    瑞博奥(广州)生物科技股份有限公司
    2025年07月15日询价
    ¥1960
    武汉琼格生物科技有限公司
    2026年02月03日询价
    文献支持
    Human PRL(CM10)
    ¥720 - 12800