Human Nectin-4(CW95)
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Human Nectin-4(CW95)

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  • ¥570 - 20800
  • SinoBio
  • 国产
  • CW95
  • 2025年12月22日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Gly32-Val351

    • 保质期

      See instructions

    • 英文名

      标签:C-Fc

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥570.0
    规格:50ug产品价格:¥1700.0
    规格:500ug产品价格:¥13870.0
    规格:1mg产品价格:¥20800.0
    产品描述
    Recombinant Human Poliovirus Receptor-Related Protein 4 is produced by our Mammalian expression system and the target gene encoding Gly32-Val351 is expressed with a human IgG1 Fc tag at the C-terminus.
    蛋白编号
    Q96NY8
    产品别称
    PVRL4; Nectin-4; Ig superfamily receptor LNIR; Poliovirus receptor-related protein 4; PRR4; LNIR
    偶联
    Unconjugated
    分子量
    61.2 KDa
    表观分子量
    75-90 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    纯度-SEC-HPLC
    Greater than 95% as determined by SEC-HPLC. (Regularly tested)
    生物活性-BLI
    Loaded Anti-Human Nectin-4 mAb-mFc(Cat#NC017) on AMQ Biosensor, can bind Human Nectin-4-Fc(Cat#CW95) with an affinity constant of 0.86 nM as determined in BLI assay.  (Regularly tested)
    生物活性-ELISA
    Immobilized Anti-Human Nectin-4 mAb-mFc(Cat#NC017) at 2μg/ml (100 μl/well) can bind Human Nectin-4-Fc (Cat#CW95). The ED50 of Human Nectin-4-Fc (Cat#CW95) is 2.79 ng/ml.  (Regularly tested)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.

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    图标文献和实验
    该产品被引用文献

    Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.

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    文献支持
    Human Nectin-4(CW95)
    ¥570 - 20800