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Human TREM-2(C15X)

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  • ¥570 - 20800
  • SinoBio
  • 国产
  • C15X
  • 2025年10月28日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:His19-Ser174

    • 保质期

      See instructions

    • 英文名

      标签:C-Fc

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥570.0
    规格:50ug产品价格:¥1700.0
    规格:500ug产品价格:¥13900.0
    规格:1mg产品价格:¥20800.0
    产品描述
    Recombinant Human Triggering receptor expressed on myeloid cells 2 is produced by our Mammalian expression system and the target gene encoding His19-Ser174 is expressed with a human IgG1 Fc tag at the C-terminus.
    蛋白编号
    Q9NZC2
    产品别称
    Triggering receptor expressed on myeloid cells 2; TREM2; Triggering receptor expressed on monocytes 2; TREM-2
    偶联
    Unconjugated
    分子量
    44.4 KDa
    表观分子量
    55-65 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    生物活性-ELISA
    Immobilized Recombinant Human TREM2 (C-Fc) (Cat#C15X) at 2μg/ml (100 μl/well) can bind Human TREM2 Antibody (5G12) (Cat#NC218). The ED50 of Human TREM2 Antibody (5G12) (Cat#NC218) is 1.99 ng/ml. (Regularly tested)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    TREM2 is a cell surface receptor of the immunoglobulin superfamily. TREM2 is a type-1 transmembrane protein that shuttles to the plasma membrane where it exerts its cell autonomous biological functions. TREM2 undergoes regulated intramembrane proteolysis (RIP). TREM2 is preferentially expressed in microglia and is functionally required for migration, cytokine release, phagocytosis, lipid sensing, ApoE binding, shielding of amyloid plaques, and microglia proliferation in the brian. Most of the functionally investigated mutations are located within the Ig-like domain of TREM2.

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    图标文献和实验
    该产品被引用文献

    TREM2 is a cell surface receptor of the immunoglobulin superfamily. TREM2 is a type-1 transmembrane protein that shuttles to the plasma membrane where it exerts its cell autonomous biological functions. TREM2 undergoes regulated intramembrane proteolysis (RIP). TREM2 is preferentially expressed in microglia and is functionally required for migration, cytokine release, phagocytosis, lipid sensing, ApoE binding, shielding of amyloid plaques, and microglia proliferation in the brian. Most of the functionally investigated mutations are located within the Ig-like domain of TREM2.

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    文献支持
    Human TREM-2(C15X)
    ¥570 - 20800