Human Fas Ligand
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Human Fas Ligand

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  • ¥1200 - 27000
  • SinoBio
  • 国产
  • C00H
  • 2025年10月28日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Pro134-Leu281

    • 保质期

      See instructions

    • 英文名

      标签:N-6His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1200.0
    规格:50ug产品价格:¥3600.0
    规格:500ug产品价格:¥18000.0
    规格:1mg产品价格:¥27000.0
    产品描述
    Recombinant Human Tumor Necrosis Factor Ligand Superfamily Member 6 is produced by our Mammalian expression system and the target gene encoding Pro134-Leu281 is expressed with a 6His tag at the N-terminus.
    蛋白编号
    P48023
    产品别称
    apoptosis (APO-1) antigen ligand 1; Apoptosis antigen ligand; APT1LG1CD95L; APTL; CD178 antigen; CD178; CD95L; CD95-L; Fas antigen ligand; Fas ligand (TNF superfamily, member 6); Fas Ligand; FASLCD95 ligand; FASLG; TNFSF6
    偶联
    Unconjugated
    分子量
    17.7 KDa
    表观分子量
    20-30 KDa, reducing conditions
    剂型描述
    Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    生物活性-BLI
    Loaded Human FAS-Fc(Cat#CX46) on Protein A Biosensor, can bind Human Fas Ligand-His(Cat#C00H) with an affinity constant of 0.34 nM as determined in BLI assay.  (Regularly tested)
    运输条件
    • The product is shipped on dry ice/polar packs.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.
    产品背景
    Fas ligand is also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its ability to induce apoptosis in target cells plays an important role in the development, homeostasis, and function of the immune system. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

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    图标文献和实验
    该产品被引用文献

    Fas ligand is also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its ability to induce apoptosis in target cells plays an important role in the development, homeostasis, and function of the immune system. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

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    文献支持
    Human Fas Ligand
    ¥1200 - 27000