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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
蛋白表达区间:Ser54-Leu206
- 保质期:
See instructions
- 英文名:
标签:Tag free
- 库存:
表达系统:E.coli
- 供应商:
上海经科化学科技有限公司
- 规格:
10ug/50ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥840.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥2520.0 |
| 规格: | 500ug | 产品价格: | ¥10080.0 |
| 规格: | 1mg | 产品价格: | ¥14400.0 |
- Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
- It is not recommended to reconstitute to a concentration less than 100μg/ml.
- Dissolve the lyophilized protein in distilled water.
- Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- The product is shipped at ambient temperature.
- Upon receipt, store it immediately at the temperature listed below.
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
- Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
- Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
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文献和实验Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2c, 3c and 4, is spatially and temporally regulated during embryonic development. FGF-4 is proposed to play a physiologically relevant role in human embryonic stem cell selfrenewal. It promotes stem cell proliferation, but may also aid differentiation depending on context and concentration, and is often included in embryonic stem cell media in vitro. FGF-4 is mitogenic for fibroblasts and endothelial cells in vitro and has autocrine transforming potential. It is a potent angiogenesis promoter in vivo and has been investigated as therapy for coronary artery disease.
and memory in aged mice via Fgf17. Nature (2022). 2. Castellano, J. M. et al. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature 544, 488–492 (2017). 3. Fame, R. M. & Lehtinen, M. K. Emergence and developmental roles
Procedure for Culturing BG01V Human Embryonic Stem Cells with Human Feeder Cell Conditioned Medium
Recombinant human FGF basic (R&D Systems, Catalog # 233-FB , 4114-TC , or equivalent) Accutase (Innovative Cell Technologies, Catalog # AT104 or equivalent) Cultrex® Basement Membrane Extract (BME) (R&D Systems, Catalog # 3433-005-01 or equivalent
Purification of Growth Factor mRNA in Renal Tissues:bFGF-2, FGF-2, TGFα, and EGFR
benign and cancerous human and animal tissues, including kidney, prostate, and bladder (3 –6 ). In some cases it has also been demonstrated to have potential as a tumor marker (7 –11 ). One group reported greater recovery of both FGF-2 protein and FGF
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