Recombinant Human IgG1 Fc/Ig g

Mutational Analysis of the Human Protein C Gene

(2 ,3 ). The gene is approximately 11 kb long and is composed of 9 exons and 8 introns. In common with factors VII, IX and X the exons encode specific structural domains of the protein C molecule. Exon 1 encodes the 5′ untranslated region, exon 2 encodes the signal

Development of Novel Major Histocompatibility Complex Class I and Class II-Deficient NOD-SCID IL2R Gamma Chain Knockout Mice for Modeling Human Xenoge

) and recombination activating 1 or 2 gene (Rag1 or Rag2 ) knockout mice bearing a targeted mutation in the gene encoding the IL2 receptor gamma chain (IL2rγ ) have been reported. The addition of the mutated IL2rγ gene onto an immunodeficient mouse stock facilitates

Introduction of human 14-3-3 proteins

of mRNA encoding human 14-3-3 protein,a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases and an endogenous inhibitor of protein kinase C.The 1,730-nucleotide sequence of the cloned cDNA contains 191 bp of a 5'-noncoding region