27-炔胆固醇-5mg-27-Alkyne Choleste

27-炔胆固醇-5mg，27-Alkyne Cholesterol-5 mg，27-炔胆固醇-5mg,27-Alkyne Cholesterol-5 mg

27-炔胆固醇-5mg-27-Alkyne Cholesterol-5 mg

产品货号：CCT-1410-5

产品规格：5mg

“这种试剂是一种含有ω-末端炔的改性脂质。 末端炔基可用于在含铜（Cu）催化剂存在下与含叠氮化物试剂的高度特异性连接反应，称为“点击化学”。 炔胆固醇代表了一种通用的，灵敏的，易于使用的工具，用于跟踪细胞胆固醇代谢和定位，因为它允许多种检测方法，包括质谱法和荧光显微镜。“

This reagent is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry’, in the presence of a copper-containing catalyst.27-Alkyne cholesterol is accepted by cellular enzymes from different biological species (Brevibacterium, yeast, rat, human) and these enzymes include cholesterol oxidases, hydroxylases, and acyl transferases that generate the expected metabolites in in vitro and in vivo assays. Using fluorescence microscopy, researchers can study the distribution of cholesterol at subcellular resolution, detecting the lipid in the Golgi and at the plasma membrane, but also in the endoplasmic reticulum and mitochondria.In summary, alkyne cholesterol represents a versatile, sensitive, and easy-to-use tool for tracking cellularcholesterol metabolism and localization as it allows for manifold detection methods including mass spectrometry, and fluorescence microscopy.

27-炔胆固醇-5mg-27-Alkyne Cholesterol-5 mg-20°C.

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