Biotin Picolyl Azide-25 mg-Bio

Biotin Picolyl Azide-25 mg，Biotin Picolyl Azide-25 mg，Biotin Picolyl Azide-25 mg,Biotin Picolyl Azide-25 mg

Biotin Picolyl Azide-25 mg-Biotin Picolyl Azide-25 mg

产品货号：CCT-1167-25

产品规格：25mg

Biotin Picolyl Azide是一种先进的生物素探针，其结合了铜螯合基序，以提高反应位点处Cu(I)的有效浓度，从而提高CuAAC反应的效率，从而实现更快和更生物相容的CuAAC标记。据报道，与常规叠氮化物相比，信号强度增加高达40倍。

Biotin Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boosted the efficiency of the CuAAC reaction resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides was reported.Biotin Picolyl Azide is an advanced azide probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boost the efficiency of the CuAAC reaction, resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides was reported.In addition, the use picolyl azides instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling, significantly improving biocompatibility of CuAAC labeling protocol.In summary, the introduction of a copper-chelating motif into azide probe leads to a substantial increase in the sensitivity and reduced cell toxicity of CuAAC detection alkyne-tagged biomolecules. This will be of special value for the detection of low abundance targets or living system imaging.

Biotin Picolyl Azide-25 mg-Biotin Picolyl Azide-25 mg-20°C. Desiccate

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