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- MedChemExpress(MCE)
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- 2025年12月05日
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货期：询盘
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MedChemExpress LLC
- CAS号：
2361384-14-5
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Neuroinflammatory-IN-2
产品活性：Neuroinflammatory-IN-2 是一种有效的抗神经炎症剂，对 MAO-B 的 IC50 为 10.30 μM，25 μM 时能抑制 96.33% 的 Aβ1-42 聚集。Neuroinflammatory-IN-2 在 H2O2 诱导的 PC-12 细胞损伤中具有神经保护作用。Neuroinflammatory-IN-2 还具有生物金属螯合能力、抗氧化活性、抗神经炎症活性和适当的血脑屏障通透性 (BBB)。Neuroinflammatory-IN-2 可用于阿尔兹海默症的研究。
产品来源： www.medchemexpress.cn/neuroinflammatory-in-2.html
研究领域：Neuronal Signaling
作用靶点：Monoamine Oxidase | Amyloid-β
In Vitro: Neuroinflammatory-IN-2 (compound 7i) (1 and 10 μM) dramatically increases the viability of H2O2-treated PC-12 cells by 70.2% and 81.6% at 1 and 10 μM, respectively.Neuroinflammatory-IN-2 (0.5, 2.5 and 10.0 μM) inhibits NO expression in LPS-stimulated BV-2 cells by 32.4%, 46.7% and 57.2% at the concentration of 0.5, 2.5 and 10.0 μM respectively; and inhibits TNF-α by 35.8%, 53.1% and 76.5%, respectively.
相关产品：DAPT | β-Aminopropionitrile | β-Amyloid (25-35) | Thioflavin T | β-Amyloid (1-42), human TFA | FPS-ZM1 | Rutin | Colivelin TFA | Rosmarinic acid | Azeliragon | Santacruzamate A | Tranylcypromine hemisulfate | 20(S)-Ginsenoside Rg3 | Ginsenoside Rg1 | β-Amyloid (1-42), (rat/mouse) | Clorgyline hydrochloride | GSK-LSD1 dihydrochloride | Methylene Blue | Tolcapone | Hypericin | Methoxy-X04 | Aducanumab | Paeonol | Selegiline hydrochloride | Geniposide | Pargyline | Semagacestat | Notoginsenoside R1
产品活性：Neuroinflammatory-IN-2 是一种有效的抗神经炎症剂，对 MAO-B 的 IC50 为 10.30 μM，25 μM 时能抑制 96.33% 的 Aβ1-42 聚集。Neuroinflammatory-IN-2 在 H2O2 诱导的 PC-12 细胞损伤中具有神经保护作用。Neuroinflammatory-IN-2 还具有生物金属螯合能力、抗氧化活性、抗神经炎症活性和适当的血脑屏障通透性 (BBB)。Neuroinflammatory-IN-2 可用于阿尔兹海默症的研究。
产品来源： www.medchemexpress.cn/neuroinflammatory-in-2.html
研究领域：Neuronal Signaling
作用靶点：Monoamine Oxidase | Amyloid-β
In Vitro: Neuroinflammatory-IN-2 (compound 7i) (1 and 10 μM) dramatically increases the viability of H2O2-treated PC-12 cells by 70.2% and 81.6% at 1 and 10 μM, respectively.Neuroinflammatory-IN-2 (0.5, 2.5 and 10.0 μM) inhibits NO expression in LPS-stimulated BV-2 cells by 32.4%, 46.7% and 57.2% at the concentration of 0.5, 2.5 and 10.0 μM respectively; and inhibits TNF-α by 35.8%, 53.1% and 76.5%, respectively.
相关产品：DAPT | β-Aminopropionitrile | β-Amyloid (25-35) | Thioflavin T | β-Amyloid (1-42), human TFA | FPS-ZM1 | Rutin | Colivelin TFA | Rosmarinic acid | Azeliragon | Santacruzamate A | Tranylcypromine hemisulfate | 20(S)-Ginsenoside Rg3 | Ginsenoside Rg1 | β-Amyloid (1-42), (rat/mouse) | Clorgyline hydrochloride | GSK-LSD1 dihydrochloride | Methylene Blue | Tolcapone | Hypericin | Methoxy-X04 | Aducanumab | Paeonol | Selegiline hydrochloride | Geniposide | Pargyline | Semagacestat | Notoginsenoside R1
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Neuroinflammatory-IN-2,2361384-14-5
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